Ebola virus fisiopatologia pdf

Ebola virus disease is one of the most deadly ailments known to mankind due to its high mortality rate up to 90% accompanying with the disease. One of the deadliest of epidemic viral diseases, ebola virus disease evd has, since its 1976. In comparison with earlier ebola outbreaks mortality have been higher 80 90 percent, but number of cases was a thousand times lower. Infects dentritic cells which help to display signal of infection on their surface to activate tlymphocyte white blood cells bodys response against.

Zika virus is a mosquitoborne virus that causes mild illness in adults, but has been linked with microcephaly in newborns. The mucinliked region of the ebola virus envelope play a significant role in viral infection in nonhuman primates and. In 2014, west african countries guinea, liberia, and sierra leone. Marburgvirus infections ebola and marburg virus disease, ebola and marburg hemorrhagic fever, african hemorrhagic fever in africa. Ebola virus disease evd is one of numerous viral hemorrhagic fevers. It is a severe, often fatal disease 50%90% fatality in humans and nonhuman primates such as monkeys, gorillas, and chimpanzees. The filamentous and pleomorphic ebolavirus is enveloped nonsegmented negative strand rna virus of 19 kb in length with a mean unit length of 1,200 nm 3,4. Ebola virus, a rna virus, was discovered in 1976 as zaire ebolavirus and currently is responsible for outbreak in the west africa. Ebola virus is transmitted through direct physical contact with infected individuals. Ebola virus ev is one of the most virulent human pathogens. Ebola virus emerged in the african rainforest in 1976 from an unknown natural.

Ebola virus disease evd, also known as ebola haemorrhagic fever ehf or simply ebola, is a viral haemorrhagic fever of humans and other primates caused by ebolaviruses. Signs and symptoms typically start between two days and three weeks after contracting the virus with a fever, sore throat, muscular pain, and headaches. The ebola virus causes an acute illness, which is often fatal. The illness is characterized by internal and external bleeding which usually leads to death. Ebola haemorrhagic fever ehf is an infectious disease of animal that can be transmitted to both human and nonhuman primates. Please use one of the following formats to cite this article in your essay, paper or report. Tissue and cellular tropism, pathology and pathogenesis of. Cdc urges all us residents to avoid nonessential travel to liberia, guinea, and sierra leone because of an unprecedented outbreak of ebola. Fievre hemorra gique a virus ebola fiche technique. High concentrations of virus particles are found in bodily fluids and in the skin. Successful treatment of advanced ebola virus infection with t705 favipiravir in a small animal model. Lhote reservoir naturel du virus ebola reste inconnu. The current outbreak in west africa is the largest and the most complex ebola outbreak since the disperse was first discovered in 1976.